LVACS Meeting Dates for 2008-2009 Academic Year

Next Meeting:

803rd Meeting of the LVACS
Lafayette College

Date:        September 24, 2008
Location:    Faculty Dining Hall, Lafayette College
Reception:    5:30, cheese and fruit
Dinner:    6:00
Meeting:    At the conclusion of dinner
Talk:        At the conclusion of the meeting, Hugel Science Center, Jaqua Auditorium  (Rm 103)
Menu:     Chicken Cordon Blue or Beef Brisket, Roast Garlic Potatoes, Fresh Green Beans, Coffee/Tea/Soda, Chocolate Layer Cake; Vegetarian Option- Portabello Stacks.
Cost:        members $20, students & retirees $10
Contact:    Debbie Bastinelli at 610-330-5213 or bastined@lafayette.edu by September 19
Directions:    On the web at http://www.lafayette.edu/community/directions.html

Speaker:    Scott McN. Sieburth

Dr. Scott McN. Sieburth is a professor of chemistry at Temple University. Scott received his BS degree from Worcester Polytechnical Institute in 1977 and his PhD from Harvard University in 1983. He worked for FMC Corporation for seven years in their Agricultural Chemical group. Before he moved to his present position at Temple University, he was professor of chemistry at SUNY-Stony Brook. He has diverse interests in organic chemistry, especially the [4+4] photocycloaddition reaction, and the synthesis and biological activity of silanediols (http://astro.temple.edu/~sieburth/). Scott received the 2008 Philadelphia Organic Chemists' Club Award in recognition of his outstanding contributions to organic chemistry and service to the scientific community.


Abstract

Using Silicon to Design New Pharmaceuticals
   Silicon is the second most abundant element, and the element closest to carbon in its properties.  Despite more than a century of organosilane research, only two silanes are produced commercially because of their biological activity, with silicon replacing a quaternary carbon.  Unlike carbondiols (X=C) that dehydrate to ketones, silanediols (X=Si) do not dehydrate to give silanones.  We have employed this property to design protease inhibitors where a silanediol mimics a hydrated amide carbonyl.  These are more complex than any silanediols previously prepared and they have stimulated a broad investigation of organosilane chemistry.
   Protease inhibitors are an important class of drugs, applicable to almost any disease.  Our silanediols have been found to be reliable protease inhibitor design components, leading to low nanomolar inhibitors of an aspartic protease (HIV protease) and metalloproteases (thermolysin, angiotensin-converting enzyme).







On Deck

804th Meeting of the LVACS
Lehigh University

Date:        November 12, 2008
Location:    Lehigh University
Times and rooms TBA

Strengthening our Academic Foundations:
Report from an NSF ADVANCE Project On the Status of Women Chemistry Faculty in Doctoral Granting Universities

Sally Chapman, Professor of Chemistry, Barnard College

Concerned by the paucity of tenured women faculty members in doctoral granting universities, the ACS with the financial assistance of an NSF Grant undertook Project Progress.   Dr. Chapman served as PI on the grant and supervised the study. Written surveys and oral interviews in focus groups and were conducted with 877 men and women, including administrators, faculty members, postdoctoral associates, and graduate students, during one-day site visits at chemistry and chemical engineering departments in 28 Ph.D.-granting institutions.  A preliminary review of the perceptions of the climate for women scientists based on the data collected during these visits has been completed.  Discrimination on both the individual and institutional level still persists, and changing this reality presents a serious challenge to advocates of gender equity.  Some recommendations are offered by the team which performed the study.

Dr. Sally Chapman was educated at Smith College and received her PhD from Yale.  After postdoctoral experiences at UC Irvine and UC Berkeley she joined the faculty of Barnard where she has served multiple terms as Department Chair and has been the holder of the Ann Whitney Olin professorship.  Sally has also chaired the ACS Committee on Professional Training and the Petroleum Research Fund Advisory Board. She has more than 30 publications mostly on the thermodynamics and kinetics of gas phase reactions. 





Past Meetings:

Please note:  Retirees and students may attend meetings at half price.  Should a retiree wish to pay full price the additional funds will be donated to the scholarship fund


CANCELLED! No Meeting
May Meeting Announcement:

804th LVACS Meeting:  
East Stroudsburg University at
Barley Creek Brewing Co
2nd Annual Pub Night - Year End Celebration!
Spouse’s Night!

Date: Tuesday, May 13th



Social:  6:00-7:30 PM - Barley Creek Back Deck- Open Bar - Complimentary beer and house wines 6:00-8:00 PM (other alcoholic beverages available as cash bar).   Jalapeno Pockets, Bruschetta, Crake Cake Bites, Cheese and Crackers,  Wings. Shuffle board, darts, chess and other games available.  Come have fun and let off some steam!

Beer Tasting:  7:00 PM - The Brewmaster of Barley Creek Brewing Company will lead us in sampling the fine beers the brewery has to offer.  Discussion of brewing ingredients and techniques will make this worth the drive!
Brewery Tours:  Throughout the evenign with the BCB Brewmaster

Dinner: 7:30 PM - Newly remodeled Barley Creek Back Deck
Menu: House salad, Choice of:
8 oz top sirloin topped with sautéed mushrooms, served with mashed potatoes and seasonal vegetables, Chicken Parmigiana served over linguini Penne Ala Vodka served with Garlic Bread, Dessert - Stout Cheesecake or Apple Pie
 
Meeting: Business meeting during dinner

Cost: $28, spouses, students and retirees $18
Contact:  Michelle Jones-Wilson by 4PM, Friday May 9.  Please provide choice of entree and affiliation.  mjwilson@po-box.esu.edu or 570-422-3703 - email contact preferred.
Directions: Barley Creek Brewing Company, Sullivan Trail & Camelback Road, Tannersville, PA http://www.barleycreek.com/find_us/index.shtml

About The Barley Creek Brewing Co: 

Located in Tannersville, right off route 80's exit 299 in between the Crossings Outlet Stores and Camelback Ski area (Camelbeach Water Park, Barley Creek is the Pocono Mountains' Original Brewpub and Restaurant, where you can always find great food, freshly brewed beer, a comfortable atmosphere, friendly people, and a unique place to kick back, relax and have a great time. Bring your friends, bring your family, bring your friends' families. Cheers!



803rd   LVACS Meeting:  
Moravian College
Student Awards and Undergraduate Poster Session

Date: Tuesday, April 22
Location: Moravian College - North Campus
Reception:  5:00 – 6:15 pm, Lobby Collier Hall of Science
Dinner:  6:15 pm – UBC Room, Haupert Union Building
Meeting and Student Awards Presentation: 7:30 pm Dana Lecture Hall, Collier Hall of Science
Talk: At the conclusion of the meeting - Dana Lecture Hall, Collier Hall of Science
Menu:  Buffet featuring Baked Chicken Breast with Pineapple/Orange Sauce and  Pasta Primavera
Cost:  members $20, students & retirees $10
Contact: LouAnn Vlahovic by Noon, Thursday, April 17th.  Please include your name, affiliation, and for students whether they are an awardee, poster presenter or both.  Registration can be made by phone (610-861-1300) or by email melnv01@moravian.edu (the last two digits are numbers). Please put LVACS Registration in the subject line. (Note: email registrations will be confirmed by a return email.)

Directions:  Directions to Moravian can be found on the web at http://www.moravian.edu/admission/directions.htm. Suggested parking is in Lots M, N, & O, along Locust Street.  A campus map is available at http://www.moravian.edu/campusMaps/north.htm.

Speaker: Madeline Jacobs, Executive Director & Chief Executive Officer ACS
Madeleine Jacobs is Executive Director and Chief Executive Officer of the American Chemical Society (ACS). As Executive Director and CEO, Jacobs has worked closely with the ACS Board of Directors, ACS volunteers and members, and the Society’s nearly 2,000 employees to help reinvent ACS and prepare it to serve its members and the chemical profession during a time of radical change in the chemical enterprise.  She is working closely with other organizations around the world to enhance ACS collaboration in the chemical sciences.

Jacobs received a Bachelor of Science degree in chemistry at George Washington University (with honors and distinction) in 1968.  She completed course work for a Master’s Degree in organic chemistry at the University of Maryland in 1969. Jacobs received an honorary Doctor of Science from George Washington University in 2003.
  
Prior to her selection by the ACS Board of Directors as Executive Director and CEO, Jacobs served for eight and a half years as Editor-in-Chief of Chemical & Engineering News magazine, the weekly newsmagazine of the chemical world published by ACS, and two years as Managing Editor. She has held other senior management positions in a wide variety of scientific and educational organizations including the National Institutes of Health, the National Institute of Standards and Technology, and the Smithsonian Institution, where she served as the director of Public Affairs at the world’s largest museum complex.
  
Major honors include the Smithsonian Institution Secretary’s Gold Medal (1993), the New York Academy of Sciences Women History Month Award (2001), the 75th Canadian Society for Chemistry Conference Lecturer (2002), the ACS Award for Encouraging Women into Careers in the Chemical Sciences (2003), and the American Crystallographic Association Public Service Award (2004). A much-honored science journalist, she has also received more than three dozen awards for outstanding science writing from national organizations. She is a Fellow of the American Association for the Advancement of Science, a member of the ACS Board of Directors, and a founding member of the Board of the Rosalind Franklin Society, dedicated to promoting women in the sciences. She is also a member of the Board of Governors of the New York Academy of Sciences.

Jacobs’ professional interests include trends in the chemical industry, the public image of chemistry, employment trends, minority representation, and gender equality of scientists. She has given speeches on these topics for more than 35 years and is a sought-after speaker.

Talk:
    “Improving people’s lives through the transforming power of chemistry.” 
Chemistry remains the unifying and enabling science to help solve the world’s most pressing problems:  ensuring sufficient energy, clean water, health care, security, and food, while achieving a sustainable planet.  As long as these challenges exist, chemists will be essential to providing solutions. The American Chemical Society is dedicated to providing chemists of all ages with the lifelong learning tools, programs, and services that will ensure a rewarding career while fulfilling the ACS vision, “Improving people’s lives through the transforming power of chemistry.” 


802nd   LVACS Meeting - High School Teacher's Night:  
Lafayette College

Date: Friday, March 28
Location: Lafayette College
Reception: 6:00 PM, 102 Phenning - Wilson Room Please note this is a new location!
Dinner: following reception
Meeting: following dinner
Talk:  8:00 PM 224 Oechsle Lecture Hall  Please note this is a new location!
Menu:  Grilled Flank Steak, Herb Crusted Chicken, Eggplant Roulade
Cost: Members ($20.00), Student Members ($5.00), Guests & Non-Members ($25.00)
Contact: Mike Popule, (610) 481-6677 populemp@airproducts.com
Directions:  visit the Lafayette College website at www.lafayette.edu

Speaker: Professor John Chen, Dean Emeritus Lehigh University

Talk:     The World's Energy and Environmental Challenges

Daily we see headlines, news articles, and commentaries about energy and environmental issues.  Political candidates all propose to “address” the problems,   What are the facts behind the headlines?   What are the fundamental parameters that will determine the future state?   Is there truly a problem?   Is so, what are some potential fall-outs?  Can conservation and/or alternate energy sources be the answer?    We’ll try to get a grasp on these questions, and speculate together about conditions that are likely to impact our lives, our professions, our society, and our environment.

801st   LVACS Meeting:  
Muhlenberg College


Reception: 5:30 - 6:00pm  in Seegers Union room 111
Dinner: 6:00pm
Meeting: 7:00 pm  in Trumbower 130
Talk: At the conclusion of the meeting
Menu: Chicken Supreme, or Sesame Beef with Asian vegetables
Cost: $20.00 members and guests; students and retirees $10.00
Contact: LuAnn Feist, 484-664-3260; email feist@muhlenberg.edu by noon Feb 25th, with name, affiliation, menu choice and phone number.
Directions:  visit the Muhlenberg website at www.muhlenberg.edu
       
Speaker: Dr. Tom Lectka
Tom Lectka obtained his B.A. from Oberlin   College in 1985.  He studied under John McMurry at Cornell, receiving   his Ph.D. in 1990.  After one year of study in Heidelberg with a   Humboldt Fellowship, he became an NIH Postdoctoral Fellow at Harvard   in Dave Evans's group.  Since 1994, he has been in the Chemistry Department at Johns Hopkins, having been promoted to Professor in  2002.  His recent awards include Dreyfus, Sloan, and J.S. Guggenheim  Fellowships, and a Merck Faculty Development Award.  His interests span problems in asymmetric and polyfunctional catalysis, solid-phase based reactions, and mechanistic chemistry.
Talk:
o-Benzoquinones constitute a diverse class of reactive  molecules whose asymmetric chemistry has been scantily explored.  From pure synthesis to medicine to biology, o-benzoquinones play  important and mechanistically interesting roles.  In this talk, we  wish to present new catalytic, asymmetric reactions of o-benzoquinones, spanning the reactivity spectrum from simple o- quinones to benzoquinone imides and dimines, as well as o-quinone
methides.  These reactions give rise to useful products such as alpha- hydroxyesters, unusual alpha-amino acid derivatives, and biologically  relevant polycyclic skeletons.  In many cases, products are produced  in almost complete enantiomeric excess, as well as in excellent  yields.

800th LVACS Meeting:  

Cedar Crest College


Date: Tuesday, January 22
Location: Harmon Hall of Peace, Cedar Crest Campus
Reception: 6 -  6:30 pm
Dinner: 6:30 -7:30 pm
Meeting: At the conclusion of dinner
Talk: At the conclusion of the meeting
Menu:
Cost: $20.00 members and guests; students and retirees $10.00.Vegetarian choice available, $18.00
Contact:   Lesley @cedarcrest.edu or 610-606-4666 ext. 3457 by noon, on January 18, 2008 .  Please given Name affiliation and phone number or e-mail.
Directions:  visit the Cedar Crest  website at www.cedarcrest.edu

Speaker: Dr. Lawrence T. Sein
   Dr. Sein is Assistant Professor of Chemistry in the Department of Chemical and Physical Sciences, Cedar Crest College, Allentown, PA. Born and raised in Philadelphia, he received his B.S. in chemistry from Charter Oak State College in 1996, M.A. in chemistry from Temple University in 1998, and Ph.D. in inorganic /physical chemistry (also from Temple) in 2000. He completed post-doctoral terms at Thomas Jefferson University and the University of Pennsylvania in computational biophysics.  He has been an invited speaker at the Technical University of Eindhoven, the Netherlands; Agricultural University of Wroclaw, Poland; and Princeton University in the United States. After having taught at Temple University, Philadelphia University, Cabrini College, and Montgomery County Community College, Dr. Sein joined the faculty at Cedar Crest College in the fall of 2005.  He teaches courses in inorganic chemistry and the quantum mechanics (Physical Chemistry II) course. He developed a new inorganic synthesis laboratory in 2005, and wrote an inorganic chemistry textbook emphasizing concepts from group theory. His research interests include conducting polymers, computational chemistry, and heterogeneous catalysis. He is co-author on 28 publications.       
Talk: Aniline Trimers with Hydroxyl Groups
   Polyaniline is a widely studied, versatile material, which conducts electricity when suitably doped. It is also effective at inhibiting corrosion of metal surfaces. Aniline trimers are convenient models for polyaniline, more effective than the polymer at corrosion inhibition, but non-conducting.  Assorted functional groups can be readily incorporated into the trimer backbone, and the results studied both experimentally and computationally. The presentation will discuss new work on the incorporation of hydroxyl groups onto aniline trimers, and the resulting effects.



799th LVACS Meeting:  
Lehigh University


Date: Wednesday, November 14
Location: Asa Packer Dining Room of the Lehigh University Center.
Reception: 6:00 PM
Dinner: 6:30 PM
Meeting: At the conclusion of dinner ~7:30 PM
Talk: At the conclusion of the meeting ~7:45 PM
Menu: Meat and vegetarian buffet featuring maple whiskey glazed chicken and Yankee pot roast with salad, mixed vegetables, baked potato, and old fashioned apple pie for dessert
Cost: $20.00 members and guests; students and retirees $10.00
Contact: JoAnn Desalvatore at (610) 758-3471 or jmd207@Lehigh.edu.  Reservations must be booked by close of work on November 5th.  Due to charges to LVACS uncancelled reservations will be billed to the member.
Directions:  consult the map and directions on  the website http://www3.lehigh.edu/about/maps/default.asp

Speaker: James J. Bohning, Department of Chemistry, Lehigh University
   James J. Bohning is professor of Chemistry Emeritus at Wilkes University, where he was a faculty member from 1959 to 1990.  He served there as chemistry department chair from 1970 to 1986 and environmental science department chair from 1987 to 1990.  He was chair of the American Chemical Society’s Division of the History of Chemistry in 1986, received the Division’s Outstanding Paper Award in 1989, and has presented more than 45 papers before the Division at national meetings of the Society.  He was on the advisory committee of the Society’s National Historic Chemical Landmarks Program from its inception in 1992 through 2001, and is currently a consultant to the committee.  Beginning in 1985 he developed the oral history program of the Chemical Heritage Foundation in Philadelphia, and was the Foundation’s Director of Oral History from 1990 to 1995.  From 1995 to 1998 he was a science writer for the News Service group of the American Chemical Society in Washington, D.C.  In May 2005 he received the Joseph Priestley Service Award from the Susquehanna Valley Section of the American Chemical Society.  He is currently a Visiting Research Scientist and CESAR Fellow at Lehigh University, where he is working on a biography of Eckley Brinton Coxe.

Talk:  Madder on the Monacacy: Eighteenth-century Moravian dye works in Pennsylvania
    When Moravian missionaries settled in 1741 on the banks of the Monacacy Creek in a town they named Bethlehem, they quickly developed a complex of more than 30 industries that included mills, tanneries and dye houses. Using natural materials such as indigo, madder, logwood and fustic, the Moravians dyed locally made fabrics, especially wool and linen, for almost a century before operations ceased. A 2007 grant from the Commonwealth of Pennsylvania will be used to stabilize the ruins of the original building, which may be the last remaining dye house of its age in the country.



798th LVACS Meeting:  
At the DaVinci Science Center in Allentown, PA
Wednesday, October 24,
6-8 PM


Celebrate National Chemistry Week with LVACS at the DaVinci Center!
www.davinci-center.org

Kids - Bring your parents or grandparents!



       
Activities for kids and private open access to the Science Center for members and their families! 

Poster Contest!
Activity Patches!
Goodie Bags!

Kids:  Make a National Chemistry Week Poster and get a prize!  Complete Activities and earn a Chemistry Activity Patch!
Goodie bags for the kids will be available featuring Moles and all kinds of cool chemistry stuff!

RSVP by October 15 to Michelle Jones-Wilson, please provide the number of children who will attend and youth t-shirt size.

No kids to bring?  Come anyway!
- the Da Vinci center is fun for all ages. 
Snacks and beverages will be provided.

See the October issue of the Octagon for activity information including poster contest rules and information and Activity Patch information.  

No charge for members and their guests.





797th LVACS Meeting:  
Lafayette College
Date: September 20, 2007
Location: Faculty Dining Room, Lafayette College
Dinner:  6:00 PM
Meeting: At the conclusion of dinner
Talk: At the conclusion of the meeting
Menu:
Frenched Chicken Breast – (Sautéed with a Whole Grain Dijon Mustard Sauce), Mixed green salad served with rolls, Garlic Mashed Potatoes, Seasoned Green Beans, Vegetarian Option – Portabella Torte, (A Thick tort made from layers of portabellas, oven roasted tomatoes, spinach, fresh mozzarella and roasted peppers), Chocolate Cake, Coffee/Tea Cost:
Cost: members $15, students & retirees $10.00
Contact: Debbie Bastinelli at (610) 330-5213 or bastined@lafayette.edu bu 9/14
Directions: on the web at http://www.lafayette.edu/community/directions.html
Speaker:
Joel P. Schneider
Dr. Joel Schneider is associate professor of Chemistry at the University of Delaware. A native of Ohio, Joel received his BS from the University of Akron in 1991 and his Ph.D. from Texas A&M in 1995. He was the George W. Raiziss Postdoctoral Fellow at the University of Pennsylvania for three years. He began his independent career at the University of Delaware in 1999, working in the fields of bioorganic and materials chemistry. He has a wide range of research interests (http://www.udel.edu/chem/Schneider/) including the development of antibiotics and self-assembling hydrogels useful as tissue scaffolds. He has recently been the recipient of the DuPont Young Faculty Award and the National Science Foundation Career Award.

Talk:  De Novo Designed Peptide-based Materials
Our research interests are centered on developing biological materials for use in delivery and tissue regenerative therapies.  We are developing peptide-based hydrogels, heavily hydrated materials, which are finding use in the delivery of therapeutics (e.g. small molecules, biomolecules, and cells) and as extracellular matrix substitutes.  Specifically, we have designed “smart” peptides that undergo sol-gel phase transitions in response to biological media enabling minimally invasive delivery of the material in-vivo. When dissolved in aqueous solutions, these peptides exist in an ensemble of random coil conformations rendering them fully soluble.  The addition of an exogenous stimulus results in peptide folding into  -hairpin conformation.  This folded structure undergoes rapid assembly into a highly crosslinked hydrogel network whose nanostructure is defined and controllable.  Peptides can be designed to fold and assemble in response to changes in pH or ionic strength, the addition of heat or even light.  In addition to these stimuli, DMEM cell culture media is able to initiate folding and consequent self-assembly. DMEM-induced gels are cytocompatible towards NIH 3T3 murine fibroblasts, mesenchymal stem cells, hepatocytes, osteoblasts and chondrocytes.  As an added bonus, many of these hydrogels possess broad spectrum antibacterial activity suggesting that adventitious bacterial infections that may occur during surgical manipulations and after implantation can be greatly reduced.  Lastly, when hydrogelation is triggered in the presence of a therapeutic, gels become impregnated with the therapeutic.  A unique characteristic of these gels is that when an appropriate shear stress is applied, the gel will shear-thin, becoming an injectable low viscosity gel.  However, after the application of shear has stopped, the material quickly self-heals producing a gel with mechanical rigidity nearly identical to the original hydrogel. This attribute allows therapeutic-impregnated gels to be delivered to target tissues via syringe where they quickly recover complementing the shape of the tissue defect.  Therapeutic release, whose rate can be possibly controlled, follows.  If cells have been impregnated into the gel, this shear-thin delivery method is a convenient way to introduce cells to wound sites.
     In addition to gel design, we are also interested in designing peptides that fold into bioactive conformations at material surfaces such as hydroxyapatite.  For these peptides, the material surface triggers intramolecular folding.  This allows function to be potentially turned on with spatial resolution only at the material’s surface.


796th LVACS Meeting  - PUB NIGHT!

East Stroudsburg University
At Barley Creek Brewing Company

Bring your significant other !
Date: Tuesday, May 15th

Social:  6:00-7:30 PM - Barley Creek Back Deck- Open Bar - Complimentary beer and house wines (other alcoholic beverages available as cash bar).  Wings, Jalapeno Poppers, Assorted Cheese and Crackers and Stuffed Celery.  Shuffle board, darts, chess and other games available.  Come have fun and let off some steam!

Beer Tasting:  7:00 PM - The Brewmaster of Barley Creek Brewing Company will lead us in sampling the fine beers the brewery has to offer.  Discussion of brewing ingredients and techniques will make this worth the drive!
Brewery Tours:  Throughout the evenign with the BCB Brewmaster

Dinner:    7:30 PM - Barley Creek Back Deck
Menu: House salad, Choice of:
8 oz top sirloin topped with sautéed mushrooms, served with mashed potatoes and
seasonal vegetables OR  Cajun grilled salmon filet, served with rice and topped with a creamy dill sauce, Veg option - Penne a la Vodka with garlic bread
Dessert - New York cheese cake

Cost:  $26, spouses, students and retirees $18

Contact: Michelle Jones-Wilson by 4PM, Monday May 7.  Please provide choice of entree and affiliation.  mjwilson@po-box.esu.edu or 570-422-3703 - email contact preferred.
Directions: Barley Creek Brewing Company, Sullivan Trail & Camelback Road
Tannersville, PA 18372, 570.629.9399; http://www.barleycreek.com/find_us/index.shtml


About Barley Creek Brewing Co
Located in Tannersville, right off route 80's exit 299 in between the Crossings Outlet Stores and Camelback Ski area (Camelbeach Water Park, Barley Creek is the Pocono Mountains' Original Brewpub and Restaurant, where you can always find great food, freshly brewed beer, a comfortable atmosphere, friendly people, and a unique place to kick back, relax and have a great time. Bring your friends, bring your family, bring your friends' families. We are open every day at 11:01am, and serve dinner till about 10pm. On Friday and Saturday we are serving dinner till about 11:00pm. The bar stays open a little longer (so you can finish your fun if you ordered food just before the kitchen closed) Cheers!























795th LVACS Meeting
Moravian College - Student Poster Session and Undergraduate Student Awards Night
Students are encouraged to Attend

Date: Tuesday, April 24th
Reception and Student Poster Session:    5:00 – 6:15 pm, Lobby Collier Hall of Science
Dinner:    6:15 pm – UBC Room, Haupert Union Building
Meeting & Student Awards Presentation:  7:30 pm Dana Lecture Hall, Collier Hall of Science
Talk:  At the conclusion of the meeting - Dana Lecture Hall, Collier Hall of Science
Menu: Buffet featuring Baked Chicken Breast with Pineapple/Orange Sauce and  Pasta Primavera
Cost:  members $20, students & retirees $10
Contact: Reservations:  LouAnn Vlahovic by Noon, Thursday, April 19th.  Please include your name, affiliation, and for students whether they are an awardee, poster presenter or both.  Registration can be made by phone (610-861-1300) or by email melnv01@moravian.edu (the last two digits are numbers). Please put LVACS Registration in the subject line. (Note: email registrations will be confirmed by a return email.)
Directions: Directions to Moravian can be found on the web at http://www.moravian.edu/admission/directions.htm. Suggested parking is in Lots M, N, & O, along Locust Street.  A campus map is available at http://www.moravian.edu/campusMaps/north.htm.

Speaker: Les McQuire
Les McQuire was born in Dundee, Scotland and completed both his undergraduate degree and PhD at his home town University.  He received a Fulbright Scholarship to travel to the University of Texas at Austin where he carried out Post-doctoral work with Prof. Phil Magnus culminating in the total synthesis of Strychnine.   Les then moved to Ciba Pharmaceuticals (now part of Novartis) in 1992 where he was part of the Arthritis and Bone Group.  He has initiated and led several projects including the Novartis Cox-2 and MMP efforts.  In 2003 he switched to the Cardiovascular disease area and help build the Novartis chemistry group in Cambridge, MA.  Les is very active in ACS, having chaired the North Jersey Section, and is currently a councilor for that section.  He is active in several ACS Divisions and the Royal Society of Chemistry.
Talk:  Drug Discovery: A Life in a Day
The talk with provide an overview of drug discovery, the challenges and opportunities.  It will also discuss how research is carried out and scientists interact in an industrial setting.  The talk will end with a discussions of "Lessons Learned Down on the Pharm(a)", common sense thoughts that are as relevant for our job searches, careers and lives today as they were to our great great grandparents "down on the farm".

794th LVACS Meeting
DeSales University - High School Teacher's Night


Date: Friday, March 23rd
Reception:  5:15 PM, Trexler Room
Dinner:    6:15 PM, Trexler Room
Meeting:  7:15 PM , Trexler Room
Talk: Trexler Room, at the conclusion of the meeting
Menu: Reception - assorted cheeses and crackers, fresh strawberries and grapes, nonalcoholic champagne, and assorted sodas  Dinner - salad, baked ham, white fish with fresh, tomatoes and spinach, garnish, chicken medallions, pasta, rice pilaf, fresh green beans, baby carrots with cinnamon butter, tarismu, chocolate cheese cake, strawberry shortcake and beverages
Cost:  $ 18.50, spouses, students and retirees $10.00
Contact: Reservations are made with Mrs. Renee Fair at {610} (282-1100, Ext.1386) or Renee.Fair@desales.edu
Reservation deadline: Tuesday, March 20, 2007, at 4:00 p.m.
Directions:

Speaker: Mr. Gerard Caprio, M.S.
Mr. Caprio is a Forensic Scientist I at theNew Jersey State Police – Office Of Forensic Sciences, Central Regional Laboratory.  He received his Master of Science degree (M.S.) in Biotechnology from  William Paterson University of New Jersey. Wayne, NJ in 2001 and a  Bachelor of Science Degree in Biology.  and Chemistry from DeSales University in 1999.

Talk:   A Killer Presentation: Forensics Utilizing Chemistry and Mitochondrial DNA Biology.

In forensic cases where nuclear DNA testing is not an option due to the nature of the evidence, it can be beneficial to pursue mitochondrial DNA testing.  Due to its abundance in our cells, mitochondrial DNA can be tested in samples that lack cellular material such as teeth, bones, and hair shafts. Since crime scenes reveal evidence of this nature, its demand in forensics has escalated, which consequently, has caused a backlog for cases requiring mitochondrial DNA testing. For that reason, the FBI decided to establish a program that would alleviate the backlog for mitochondrial DNA case submission while offering no cost testing to outside agencies. This presentation will outline the FBI Regional Mitochondrial DNA Program, discuss mitochondrial Biology and its forensic applications, and also discuss chemical principles relevant to mitochondrial DNA analysis.


793rd LVACS Meeting
Cedar Crest College

Date: Tuesday February 27, 2007
Reception: 6:00-6:30 PM  in Alcove A of the Tompkins College Center
Dinner: 6:30-7:30 PM in the 1867 Room of the Tompkins College Center
Meeting: 7:30  in the 1867 Room  with the talk at the conclusion of the meeting
Talk: At the conclusion of the meeting
Menu: Beef Burgundy or a vegetarian option is available upon request
Cost:  $ 15.00  , spouses, students and retirees $8.00
Contact: Lesley Jones at 610-606-4666  ext 3457 or Lesley@cedarcrest.edu by noon on Wednesday Feb 21, 2007
Please give your name, affiliation and phone number.

Directions:  consult the map and directions at http://www.cedarcrest.edu/Redesign/Home%20Page/ataglance_frameset.asp

Speaker: Thomas A. Brettell, Ph.D., D-ABC

Dr. Brettell is Assistant Professor in the Chemical and Physical Sciences Department at Cedar Crest College.   Tom received his BA degree (1973) in Chemistry from Drew University, Madison, NJ; a MS degree (1975) in Chemistry from Lehigh University in Bethlehem, PA; and a Ph.D. degree (1987) in Analytical Chemistry from Villanova University, Villanova, PA.  Dr. Brettell joined Cedar Crest College in the fall of 2006.  He previously served as Director of the New Jersey State Police Office of Forensic Sciences, where he oversaw the operation of the State’s four regional forensic laboratories, the Equine testing laboratory in the Meadowlands, and the DNA Laboratory in the Forensic Science Technology Complex at Hamilton, NJ.  Dr. Brettell joined the New Jersey State Police Forensic Science Bureau in 1976 as a Forensic Chemist where he worked in the Drug and Toxicology Units of the Central Laboratory (West Trenton, NJ).   In 1980, Dr. Brettell was appointed as the Technical Director of South Regional Laboratory (Hammonton, NJ), and later served as the Technical Director of the Central Laboratory until 1990 when he was assigned to the Chief Forensic Scientist’s office.  Dr. Brettell was promoted to Assistant Chief Forensic Scientist in 1993 and then to Chief Forensic Scientist in August of 1998.  In 1993, he received a commendation from the NJSP Superintendent for his work on a narcotics investigation.  For several years, Tom has taught Forensic Science in the Criminology and Justice Departments at The College of New Jersey and Rider University.  He is the past Chair of the Criminalistics Section of the American Academy of Forensic Sciences and the past President of the Chromatography Forum of the Delaware Valley.  Tom was presented the Chromatography Forum of the Delaware Valley Award in 1997 for service to the Forum and accomplishments in the field of separation science and also served on the Advisory Board of the Journal of Analytical Chemistry from 1996 to 1998.  Dr. Brettell was recently appointed to the Governor’s Advisory Council Against Sexual Violence and to the National Safety Council’s Committee on Alcohol and Other Drugs.  Dr. Brettell is a certified Diplomat of the American Board of Criminalistics and a Fellow in the American Academy of Forensic Sciences.  He also holds memberships in the New Jersey Association of Forensic Scientists (Director 1999-2000), Northeastern Association of Forensic Scientists, the Mid-Atlantic Association of Forensic Scientists, and the American Chemical Society.  Tom has numerous publications and has presented several seminars and technical presentations on various aspects of Forensic Science.

Talk:  Measuring Alcohol in Blood and Breath for Forensic Purposes - A Historical Perspective

The first scientific investigations into the fate of alcohol in the human body started about 150 years ago.  Since that time significant technical innovations have evolved to make the analysis and measurement of ethanol in biological specimens scientifically reliable for medico-legal purposes.  This presentation will discuss important events and trends in the evolution of chemical tests for alcohol intoxication.  A historical perspective of the development of methodology will be described which includes the pioneer wet chemical methods and the present state-of-the-art instrumentation.   Quantitative methods for the determination of alcohol in the blood, breath, and urine appeared early in the twentieth century.  Around 1935 in the U. S., the first instrument was developed for measuring the concentration of alcohol in a person’s breath.  After the development of the Breathalyzer around 1953, breath-alcohol testing became established for law enforcement purposes both in the U.S. and Canada. The technology of breath-alcohol testing has changed dramatically over the years from chemical oxidation and colorimetric procedures towards physicochemical techniques such as gas chromatography, electrochemical oxidation, and infrared spectrophotometry.  The classic wet-chemistry methods for blood alcohol were replaced by enzymatic procedures in the early 1950’s and in the 1960’s gas chromatographic methods began their domination.   Today, headspace GC is the mainstay in forensic blood alcohol determination as well as for the analysis of other volatiles in biological fluids.





792nd LVACS Meeting
Muhlenberg College


Date: Thursday Jan 25th
Reception: 
5:15 – 6:00 pm Great Room (room 113) Seegers Union
Dinner: 6:00 pm
Meeting:
7:00 pm Trumbower lecture hall (room 130)
Talk: At the conclusion of the meeting
Menu:
Lemon barbecue Flank steak, or Turkey Tetrazzini, or vegetarian
Cost: $20 per member or guest, $10 for students and retirees
Contact: 
Contact LuAnn Feist at 484-664-3260 or feist@muhlenberg.edu by noon on Monday Jan 22nd. Please give you name, affiliation, choice of entrée and a phone number.

Directions:   http://www.muhlenberg.edu/muhlinfo/directions.html#toBerg

Speaker: 
Phil Henderson

Dr. Henderson is Manager of the Reactive Gas Applications Group in the Materials Research Center at Air Products and Chemicals (Allentown, PA). Born and raised in Los Angeles, California, he received his B. Sc. degree from the University of California at Berkeley in 1983 and his Ph. D. in fluorine chemistry in 1987 from the University of Southern California. Upon graduation he was hired by Air Products as a Senior Research Chemist. During his 19-year career at Air Products, Phil has served as principal investigator on projects within the Specialty Gas Department involving indirect fluorination with metal fluorides, Electronic Specialty Gas analysis and purification, and surface fluorination of polyolefins with F2. In 2000, Phil transferred to the Materials Research Center where he has served as team lead for multiple projects including specialty gas separations/purifications, surface treatment and thin film deposition using low temperature atmospheric pressure plasma, and novel delivery systems for hazardous specialty gases using ionic liquids. Phil is co-inventor on 12 patents and co-author on 16 publications. Other interests include his family, writing/performing/recording music, and playing strategy games.

Talk: Ionic Liquids: Beyond the Green

Ionic liquids are materials containing only ions with a melting point below 100°C. Although known since 1914, intensive exploration of this class of compounds began about 15 years ago with the preparation of ionic liquids resistant to hydrolysis. Although originally developed as improved electrolytes, the majority of the published literature concerning these compounds focuses on their use as “green” (or environmentally friendly) solvents. Ionic liquids have been labeled as green because of their low volatility and recyclability; however, their toxicity is generally no better or worse than conventional solvents. At Air Products, we have identified a subclass of ionic liquids that exhibit weak chemical interactions with gases allowing us to develop new applications for ionic liquids as gas storage and delivery media as well as high quality absorbents. This presentation will provide an introduction to this facinating class of compounds and their applications beyond use as green industrial reaction chemistry solvents.




791st LVACS Meeting
Lehigh University - Spouse's night!


Date: Thursday November 16, 2006
Location:  Asa Packer Room, University Center
Reception: 6:00 crudite and refreshments
Dinner: 6:30 Buffet
Meeting: At the conclusion of dinner
Talk: At the conclusion of the meeting
Menu: Selections from salads, Crab Stuffed Baked Flounder with Tomato Bruschetta and Cheese Tortellini Alfredo Primavera, assorted steamed vegetables, orange rice, sunshine lemon tart dessert, tea and coffee.
Cost:  $20, spouses, students and retirees $10.00
Contact:  Please call [(610) 758-3471] to reserve your place before close of work Friday, November 10th
Directions:  consult the map and directions on  the website www.lehigh.edu

Speaker: Salvatore J. Salamone Ph.D.
Chairman and CEO, Saladax Biomedical Inc.
Salvatore J. Salamone, Ph.D., is the Chairman & Chief Scientific Officer of Saladax Biomedical. Dr. Salamone has over twenty years' experience in the healthcare and medical device industry. At Roche Diagnostics, where he served for seventeen years, Dr. Salamone's most recent position was Vice President of Research and Development from which he managed all of Roche's North American Research and Development efforts for the Laboratory Systems division. He was also responsible for establishing the Research Center of Excellence in Indianapolis, Indiana, after the acquisition of Boehringer Mannheim by Roche. Dr. Salamone's efforts during his tenure resulted in the launch of seven major reagent product lines (Abuscreen OnTrak, TesTcup, OnLine  DAT, OnLine II TDM/DAT, Fluorescent Polarization TDM  line, TesTstik, Integra DAT/TDM line) which account for over 70 FDA approved products and 200 instrument applications. Dr. Salamone is world-recognized in the field of drug monitoring with well over 100 publications, chapters, books and patents in the area. After leaving Roche, Dr. Salamone joined OraSure Technologies, Inc. as Senior Vice President, Research and Product Development where his research group was responsible for the development of a new technology with applications in the field of drug monitoring and support of the OraQuick HIV 20 minute assay. Dr. Salamone is also Founder and President of Advance BioTech Consulting, LLC, where he provides guidance and direction to the biotechnology industry in  technology assessment, strategic planning and product development. His clients include the top diagnostic players as well as multiple smaller biotech companies.  Before joining Roche Diagnostics in 1984 Dr. Salamone was a post-doctoral fellow at Oxford University, England where he studied in the area of bioorganic chemistry He received two B.S. degrees (Chemistry and General Science) from Villanova University, and his M.S. and Ph.D. degrees in Chemistry from Rutgers University.

Talk:  Advances in Chemotherapy Management: Making drugs more effective and less toxic
Maintaining a patient's blood level in a precise therapeutic range is a big part of making that pharmaceutical maximally effective for that patient.  Often in combination therapies -- where more than one drug is part of the dosage regimen -- the clearance kinetics will differ substantially.  New advances in diagnostic medicine allow monitoring to insure the patient's levels are optimum and that the chance for therapeutic benefit is thereby improved.

790th LVACS Meeting:  
Albright College
Date: Wednesday October 25, 2006
Location:
Center for the Fine Arts Mezzanine (social hour and dinner);Merner-Pfeiffer Hall of Science Room 221 (speaker).
Reception: 5:30 PM
Dinner: 6:30 PM 

Meeting: At the conclusion of dinner ~ 8:00 PM
Talk: At the conclusion of the meeting
Menu:
Assorted Bread Sticks w/ Butter, Pear Salad with Spring Greens, Sauté Chicken Breast with Artichoke Hearts and Sun dried Tomatoes* OR Grilled Fresh Fish Served with Sauce Maltaise*, Wild Rice with Pine Nuts, Stir Fry Vegetables, Chocolate/Raspberry Mousse Parfait, *Please specify a choice of entrée
Cost:  $23.00, students and retirees $12.00
Contact:
Reservation by 4:00 P.M. Wednesday October 18, 2006 through Nancy Kerper at (610) 921-7720 or Pam Artz at partz@alb.edu (E-mail is preferred with LVACS as the subject). Please specify a choice of entrée.
Directions:
Available at http://www.albright.edu/about/directions.html

Speaker:
Gaylen Bradley, Ph.D., Visiting Professor of Pharmacology and of Biochemistry and Molecular Biology Penn State College of Medicine, Hershey, PA.

Dr. Bradley came to Penn State College of Medicine as Visiting Professor of Humanities in 1999 to direct the intercampus course on Ethics in the Life Sciences.  In 2000 he also became Senior Associate Director of Research Affairs at Penn State College of Medicine, where his primary role was to create a culture of conscience throughout the Milton S. Hershey Medical Center.  He advised faculty on plans for management of personal financial interests and served as a member of the campus Conflict of Interest Review Committee until June 30, 2005 at which time he returned to active bench research.  Prior to relocating to Penn State Hershey in 1999, he was Vice President for Academic Affairs at the University of Maryland Biotechnology Institute, and Dean of Basic Health Sciences and Chair of Microbiology and Immunology at the Medical College of Virginia, Virginia Commonwealth University.  He received his baccalaureate training at Missouri State University with a BA in Chemistry and a BS in Biology.  He received his MS and PhD from Northwestern University.   He is a past chair of the SE Pennsylvania Section of ACS and is a member of the board of the Council of Scientific Society Presidents.  He is married to Judith S. Bond, who is Professor and Chair of Biochemistry and Molecular Biology, Penn State College of Medicine and immediate past president of the American Society for Biochemistry and Molecular Biology. Dr. Bradley’s research has used the tools of cell and molecular biology to study the mechanism of action of chemicals on a living system, interactions among chemicals within a living system, and interactions among living systems.  He and his associates have published 200 technical reports.  His current research is on the biologic function of metalloproteases in health and disease, in particular the interactions among the intestinal flora, the host immune system, and the genotype of the host in inflammatory bowel disease.  Dr. Bradley has lectured on various aspects of responsible conduct of research at national scientific meetings, meetings of research administrators, research universities, and undergraduate colleges.

Talk:  Issues in Scientific Ethics Today
Hardly a day passes without seeing an article in Chemical and Engineering News or the popular press about breaches in responsible conduct of research.  Charges of plagiarism have been levied at students, faculty and administrators.  Research workers have been charged with allowing their personal financial interests to influence their design, conduct and reporting of research.  Scientists, particularly clinical investigators, have been alleged to endanger human participants in clinical trials.  As a result, academic institutions, research organizations, and state and federal agencies have established rules to guide or prohibit conduct of research.  The principles that guide responsible conduct or research will be explored.  The processes for establishing regulations will be evaluated, as well as the factors that lead scientists to engage in unethical practices.  The public holds scientists in high regard.  Is the public trust warranted?  This presentation will identify some of the current issues in scientific ethics and the principles that are invoked in reports addressing specific or general behavior of members of the scientific community.

789th LVACS Meeting:  
Lafayette College
Date: September 28, 2006
Location: Faculty Dining Room, Lafayette College
Reception: 5:30 PM -6:00 PM, Assorted cheese & crackers, soda
Dinner:  6:00 PM
Meeting: At the conclusion of dinner
Talk: At the conclusion of the meeting
Menu: Tossed Green Salad with Blue Cheese & Italian Dressing, Assorted Rolls & Butter, Crabcakes, Grilled Flank Steak with a Whiskey Barbecue Sauce, Portobello & Spinach Ravioli with roasted tomato sauce (Vegetarian Option), Orzo & Wild mushroom herbs, Haricot Vert Green Beans, Dessert: Peanut Butter Pie
Cost: members $25, students & retirees $12.50
Contact: Debbie Bastinelli at (610) 330-5213 or bastined@lafayette.edu bu 9/21
Directions: on the web at http://www.lafayette.edu/community/directions.html

Speaker: Professor Jack Norton of Columbia University.
Talk:  H• Transfer from Transition Metal Hydrides. Applications to Polymers and to Synthesis
Details will be published as they become available.


On Deck !



Link to previous year LVACS meetings